Very Good
4,854 reviews
Via Cola Di Rienzo 23, Rome
What guests liked
Could be better
Modern Boutique Hotel on Rome's Best Shopping Street
The Twentyone Hotel offers a sleek stay on Via Cola di Rienzo, a prime shopping destination in Rome. Just a short stroll away from iconic landmarks like Castel Sant'Angelo and the historic center, this modern boutique hotel is the perfect blend of style and convenience.
Ultra-Modern Rooms and Dining Experience
Experience luxury in every detail with ultra-modern rooms boasting minimalist decor and top-notch amenities including LCD satellite TV, air conditioning, minibar, and complimentary WiFi. Indulge in a delightful culinary journey at the on-site restaurant offering traditional Roman and classic Italian dishes paired with a wide selection of wines and champagne.
Prime Location in Elegant Prati District
Located in the upscale Prati district, the hotel is a stone's throw away from the Vatican and Saint Peter's Basilica, making it an ideal choice for travelers interested in exploring the city's rich history. With easy access to Lepanto Metro Station and bus links to Roma Termini Train Station, your Roman adventure begins at the doorstep of Twentyone Hotel.
Book your stay now and elevate your Roman holiday experience at Twentyone Hotel.
Please note that parking spaces are limited and subject to availability. A deposit may be required at the property.
Teresa
solo_traveller · Jul 2026
Lovely hotel. Breakfast was plenty full. Very clean hotel. Its in a good location.
There was no draws in our room. I do like to unpack. We stayed or 5 nights. Had to keep socks and underwear in our hand luggage cases. That was my only fault.
Eleonora
couple · Jul 2026
Idromassaggio in camera, la colazione e una cosa non scontata la gentilezza dello staff
Khaled
solo_traveller · Jul 2026
“A great hotel in very nice location”
I loved the location, cleanliness and friendly staff. The room was comfortable and nice with good size and decent street view.
There were very small issues, the AC fan was a bit loud and the corridors had a tiny bit of some humidity smell so I think they need fresh air every now and then.. My room had a tiny bit of that smell at first but few minutes of opening the window fixed it.
María victoria
couple · Jul 2026
La ubicación . La amabilidad del personal